Genetics of the Dombrock blood group system.

In April I965, anti-Doa, an antibody defining a 'new' red cell antigen, was reported (Swanson, Polesky, Tippett, and Sanger, I965). The present paper records the results of tests with anti-Doa on samples received in this unit from October I964 until April I966. Anti-Doa reacts best by the antiglobulin test on papainized cells, but only a minority of otherwise good antiglobulin sera are suitable. The y G or y M reputations of antiglobulin sera have not, so far, provided a guide for finding a suitable reagent. A second example of anti-Doa (Webb, Lockyer, and Tovey, I966) behaves in the same way.